Resources

Research and perspective from the Sensal Health team

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New Journal of the American Academy of Dermatology · 2026

Impact of a Novel Electronic Monitor on Psoriasis Patient Adherence to Prescribed Dose Frequency and Amount: Secondary Analysis of a Randomized Trial

Shaffer BR, Lovell KK, Grenzaid JD, Zaino M, Subramanian V, Sirdeshmukh D, Wiegandt N, Richardson I, Feldman SR

Randomized trial demonstrating that electronic dose quantity monitoring improved adherence to both prescribed frequency and dose quantity in psoriasis patients on deucravacitinib. The first published randomized evidence linking sensor-verified solid oral dose measurement to clinical compliance outcomes.

psoriasis · deucravacitinib · electronic monitor · dose quantity · solid oral dosage · quantity-level monitoring · sensor-verified · gravimetric · randomized trial

Pharmacy · 2025

Validation of the Sensal Health MyAide™ Smart Dock Medication Adherence Device

Wallace D, Ganna S, Aparasu RR, University of Houston College of Pharmacy

Independent validation study confirming 100% dose quantity agreement and 99% time-of-administration accuracy for the MyAide Smart Dock across 144 actuations. Establishes weight-based medication quantity measurement as a reliable mechanism for solid oral adherence monitoring.

device validation · medication adherence · dose quantity · medication weight · gravimetric · electronic monitoring · solid oral dosage · sensor-verified · Smart Dock · compliance

Journal of Dermatological Treatment · 2024

Monitoring Adherence to Vulvar Lichen Sclerosus Treatment: A Prospective Study

Zaino ML, Pixley JN, Subramanian VM, Sirdeshmukh D, Feldman SR, Pichardo RO

First objective measurement of topical corticosteroid adherence in vulvar lichen sclerosus, capturing both timing and dose quantity of ointment dispensed using gravimetric sensor technology. Median adherence was 65%, with dose quantity deviations linked directly to lack of clinical improvement.

topical adherence · ointment · vulvar lichen sclerosus · clobetasol · dose quantity · medication weight · gravimetric · quantity-level monitoring · sensor-verified · dermatology compliance

Journal of the American Academy of Dermatology · 2023

Holiday Holidays: A Reduction in Topical Medication Adherence During the Winter Holidays

Kontzias C, Patel H, Prajapati S, Chandy R, Subramanian VM, Sirdeshmukh D, Feldman SR

Topical medication compliance declined significantly during the winter holiday period, with gravimetric monitoring revealing that most patients applied suboptimal quantities of ointment throughout the study, deviations invisible to proxy-event systems.

topical adherence · ointment · holiday · electronic monitoring · dose quantity · medication weight · gravimetric · psoriasis · atopic dermatitis · acne · quantity-level monitoring · sensor-verified

Journal of Dermatological Treatment · 2023

Patients with Vulvar Lichen Sclerosus Prioritize Education on Disease Etiology, Triggers and Treatment

Zaino ML, Pixley JN, Feldman SR

Prospective survey finding that patients with vulvar lichen sclerosus ranked disease etiology and triggers as their highest educational priorities, with support group information rated lowest. Companion study to the topical adherence measurement work from the same Wake Forest research group.

vulvar lichen sclerosus · patient education · disease etiology · topical therapy · ointment · treatment adherence · dermatology · patient preferences · compliance

JAAD Annual Meeting · September 2025

Assessing the Adherence and Clinical Outcomes of Using Multiple Topical Acne Products vs. a Single Combination Product

Yi R, Moran S, McGrath L, Majid S, Lovell K, Feldman SR, Wake Forest University School of Medicine

Randomized 12-week study measuring dose quantity and timing across one, two, and three topical acne products. Patients on a single combination product maintained adherence above 90% at both six and twelve weeks; adherence declined substantially with regimen complexity.

acne · topical adherence · dose quantity · regimen complexity · combination product · electronic monitoring · sensor-verified · dermatology compliance

JAAD Annual Meeting · September 2024

Measuring Topical Medication Adherence: Validation Study of an Electronic Monitoring Cap

Lovell K, Feldman SR, Wake Forest University School of Medicine / Sensal Health

An earlier pilot validation of the Smart Cap electronic monitoring device across 208 dispense events, confirming 99% accuracy for time of dispense and 93% agreement for medication weight within 0.5g. Smart Cap accuracy has since improved; current figures appear on the Platform page. This early work established weight-based dose quantity measurement as viable for topical adherence monitoring in clinical and research settings.

topical adherence · Smart Cap · electronic monitoring cap · dose quantity · medication weight · ointment · sensor-verified · device validation · dermatology

ISPOR Annual Meeting · Atlanta, GA · May 2024

Validation of the Sensal Health MyAide™ Smart Dock Medication Adherence Device

Ganna S, Wallace D, Aparasu RR, University of Houston College of Pharmacy

Conference presentation of the Smart Dock validation study, reporting 100% dose quantity agreement and 99% time-of-administration accuracy across 144 actuations. Published in Value in Health, Volume 27, Issue 6, S1.

Smart Dock · device validation · dose quantity · electronic monitoring · solid oral dosage · medication adherence · sensor-verified · ISPOR · health economics · outcomes research

Underlying scholarship on patient accountability and trust from the Sensal Health team.

Patient Preference and Adherence · 2017

Accountability: A Missing Construct in Models of Adherence Behavior and in Clinical Practice

Oussedik E, Foy CG, Masicampo EJ, Kammrath LK, Anderson RE, Feldman SR

Names accountability as the missing construct in standard models of adherence behavior, arguing that the social interaction between patient and provider, rather than reminders or self-efficacy alone, is what drives medication-taking. The conceptual seed for designing patient accountability into the MyAide platform.

accountability · adherence behavior · patient-provider relationship · social cognition · behavioral science · medication compliance

Patient Education and Counseling · 2022

Accountability in Reminder-Based Adherence Interventions: A Review

Salisbury KR, Ranpariya VK, Feldman SR

Literature review distinguishing accountability interventions from reminders, finding accountability is rarely built into reminder-based adherence studies despite both mechanisms improving compliance through different pathways. Supports the design rationale for accountability-driven medication intelligence rather than reminder-based engagement.

accountability · reminder interventions · adherence behavior · digital health · behavioral science · medication compliance

Journal of Dermatological Treatment · 2024

Toward a Better Understanding of Treatment Adherence: Incorporating Accountability Explicitly into the Social Cognitive Theory of Adherence Behavior

Ewulu AR, Singh R, Roberson KB, Masicampo EJ, Feldman SR

Extends Bandura's social cognitive theory of adherence by incorporating accountability as an explicit construct, providing the behavioral-science scaffolding for medication intelligence platforms built on patient-provider accountability rather than passive reminders.

accountability · social cognitive theory · Bandura · adherence behavior · dermatology · behavioral science · medication compliance

Journal of Marketing · 2002

Consumer Trust, Value, and Loyalty in Relational Exchanges

Sirdeshmukh D, Singh J, Sabol B

Foundational decomposition of trust into three structural dimensions: operational competence, operational benevolence, and problem-solving orientation. Measured across frontline and management policy levels, the framework is the structural basis of Sensal's trust architecture for medication intelligence.

trust · operational competence · operational benevolence · problem-solving orientation · relational exchanges · consumer behavior · trust architecture

Journal of the Academy of Marketing Science · 2000

Agency and Trust Mechanisms in Consumer Satisfaction and Loyalty Judgments

Singh J, Sirdeshmukh D

Unifies agency theory and trust research into a single framework for principal-agent exchanges. Written before AI agents were operational, the model maps directly to how patients form trust in medication intelligence agents acting on their behalf.

agency theory · trust · principal-agent · consumer-provider relationships · relational exchanges · trust architecture

PDF · Deck 26 pages

Shifting the paradigm of dermatology medication management

Sensal Health · April 2026